For thousands of years, herbs have been used to prevent disease, solve health problems, and treat disease. In fact, 50% of medicine in modern medicine comes from nature. Many ancient civilizations have documented herbal plants and their medicinal uses, as evidenced by the AYURVEDA system in India and the traditional Chinese Medicine System in China. And many herbs have been documented in many traditional medical systems. The classic example is the black plant, which has been used for centuries in a number of regional and national systems, including Europe, Asia, the Mediterranean, Turkey and the Middle East. Black Seed (Nigella Sativa) , also known as "Black Seed Black Seed" or "Blackcumin Black cumin" , is known in Arab countries as "blessed Seed" . Black Grass seed and black grass seed oil have been used for centuries to address a variety of health problems, such as diabetes, diarrhea, rheumatoid arthritis, appetite-stimulating and bronchitis. But in addition to these traditional applications, modern research has shown that black seed oil has many other health benefits, such as anti-cancer, anti-bacterial, anthelmintic, analgesic, anti-inflammatory, gastrointestinal, liver, cardiovascular, and antioxidant properties. SABINSA's patented black seed Oil Nigellin contains and is based on the active ingredients of thymoquinone, thymohydroquinone, ivy sapogenin and total fatty acids. The active ingredient of Nigellin, extracted by Supercritical fluid extraction, is retained to the maximum extent and has no residual solvent. Niglin M Health Effects Nigellin main health effects are anti-allergy, liver protection, anti-diabetes, anti-oxidation and anti-inflammation and so on. Anti allergy black seed oil is extracted from high quality black seed oil. Many clinical studies have shown that black seed oil has significant anti allergy effects, especially for seasonal allergies, allergic rhinitis and asthma. A clinical study of 63 children (ages 6 to 17) showed that 80% of allergic rhinitis and asthma symptoms improved. In another clinical study of 20 adults with inhalation allergy, subjective feelings and allergy symptoms improved in all subjects. Black seed oil relieves allergic symptoms in adults and children without any side effects. Nigellin "has access to allergic rhinitis in Canada, " it said. Liver protection in a rat liver ischemia-reperfusion injury experiment, black seed oil significantly improved liver biochemical parameters, such as serum L-Aspartic Acid, Alanine aminotransferase and dehydrogenase levels, total antioxidant efficacy and total oxidative stress. Black seed oil protects liver tissue from heavy metals such as lead and reduces Lipid peroxidation. In many diabetes models, black seed oil, as a mature black seed extract, and its thymoquinone have positive effects on Serum Insulin and Blood Glucose concentration. Biochemical studies have shown that black seed oil and thymoquinone can combat type diabetes by reducing oxidative stress and protecting the integrity of pancreatic cells. The antioxidant activity of thymoquinone in black seed oil was studied in vitro. In animal studies, black seed oil has been shown to inhibit oxidative and Lipid peroxidation damage to the liver by increasing levels of Glutathione, Catalase, and SOD. Anti-inflammatory effect black seed can solve a variety of inflammatory problems, and anti-inflammation is a lot of health issues of concern. In a lipopolysaccharide induced macrophage assay, black seed oil showed potent anti inflammatory effects and inhibited the release of Nitric Oxide IC50 at 6.2 GML. Clinical Studies in humans have shown that allergic rhinitis oil improves nasal congestion, itching, runny nose, sneezing and turbinate hypertrophy in patients after 2 weeks of use. Other studies have shown that black seed oil inhibits inflammatory factors such as IL-1, IL-6, transcription factors and nuclear factors. The Nigellin n currently available from SABINSA comes in three sizes: amber, Agate and Pearl. All sizes contain thymoquinone, thymoquinone, sapogenin and total fatty acids. Amber, grade oil, is extracted using Supercritical fluid extraction technology and can be used in soft capsules. Solid dosage form products, you can use agate grade and Pearl Grade. Agate grade for the removal of oil-based components of the light gray powder. The Pearl grade is a kind of white powder after removing the oily component.